Dosing to Meet
Assess Risk. Consider Time. Leverage Orenitram.
Reaching a necessary dose exposure is important to achieving clinical improvement, but individual patient needs may vary.1 Selecting the appropriate dosing approach may help you and your patients reach this goal.
The Orenitram Titration Kit
For intermediate-risk patients—An all-in-one kit that helps simplify the titration process and build confidence as patients work to reach necessary exposure.1
Transitioning From Remodulin to Orenitram
For hemodynamically and clinically stable patients—An established plan for transitioning appropriate patients from Remodulin® (treprostinil) Injection to Orenitram.
Did you know that eligible patients may start treatment on the Orenitram Titration Kit at no cost for up to 90 days?Learn More >
United Therapeutics does not provide medical advice. Adverse effect management strategies should be addressed in accordance with the Orenitram Full Prescribing Information and your clinical judgment.
Dosing and AE Management as a Team
Franck Rahaghi, MD, and Starlet Harrimon, RN, discuss how they work with patients to plan for expected adverse effects with Orenitram.
Dosing With Orenitram
5 tablet strengths for flexible dosing
Multiple tablet strengths provide dosing flexibility to meet your patient’s unique clinical needs, and allows them to continue to titrate to reach maximum clinical benefit.1*
*Maximum labeled dose for Orenitram is 120 mg TDD.1
Support a TID dosing schedule
Orenitram is best tolerated TID every 8 hours with food, as this may help to reduce peak-to-trough fluctuations.1
Help proactively manage and plan for expected adverse effects1,2
Reaching a therapeutic dose may be challenging for some patients. Most discontinuations occur within the first few months and may be due to adverse events.3See Strategies for Managing Adverse Effects >
“What I would tell someone who’s starting to titrate on Orenitram is to give yourself time to get used to the side effects, because for me it got better. There is light at the end of the tunnel.”
Frequently Asked Questions
United Therapeutics does not provide medical advice. Adverse event management or dosing strategies should be dealt with in accordance with the Orenitram Full Prescribing Information and your clinical judgment.
Orenitram Titration Kit
Discover how the Titration Kit may help your patient start Orenitram with confidence.
Transitioning to Orenitram
See why stable patients on parenteral prostacyclin who switch to Orenitram may transition successfully.
A Confident Start
Read about the steps you and your patient may take to help them feel confident as they begin taking Orenitram.